Hi, Sarah

Big week. The segmented email A/B test we shipped last sprint produced a 2.4x lift in qualified donor outreach versus the prior month's batch sends. We rebuilt your donor list around three personas — research advocates, familyofpatient supporters, and policy donors — and the personamatched subject lines outperformed generic ones by a wide margin on every cohort. We also cleaned up the unsubscribe handling so the new segments stay healthy as you grow them. Sends from the policy persona had the highest replytothread rate (12 conversations started this week alone), so we'd suggest leaning into that thread next sprint with a research roundup. Net: this saves you about 5 hours a week on list pulls and 2 hours on subjectline guesswork — and your engaged donor pool grew by 23 names without any ad spend.